Ross: Prescribing

at a Glance

Sarah Ross

Multiple Choice: Therapeutic drug monitoring

Question 1.

An 87-year-old woman has been taking digoxin for atrial fibrillation for 15 years, but now complains of nausea and reduced mobility. Her current dose of digoxin is 187.5 micrograms orally daily. Her digoxin level is 3.0 nmol/L (therapeutic range 1.0-2.6 nmol/L).

Which of the following is the most appropriate course of action?

A. Continue the current dose
B. Prescribe digoxin-specific antibody fragments
C. Reduce the dose
D. Stop the digoxin and restart at a lower dose once the level is therapeutic
E. Stop the digoxin and restart at the same dose once the level is therapeutic
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