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Multiple Choice: Chapter 66 Learning disability and autism Question 1. Regarding Down's syndrome which of the following is correct? (a) Most cases are caused by unbalanced translocation of chromosomes 14 and 21 (b) Girls with Down's syndrome are infertile due to their trisomy 21 (c) 88% of cases of non-disjunction arise from the maternal gamete and 5% from paternal gamete (d) Children with mosaic Down's syndrome do not have the characteristic heart defects of children with full trisomy 21 (e) Most babies with Down's syndrome are born to mothers age >35