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Multiple Choice: Chapter 11 Pharmacodynamics II Question 1 Which of the following definitions describes an antagonist? A A substance that binds to a receptor and causes a response B A substance that binds to a receptor and causes no response C A substance that binds to a receptor and causes a smaller response than that produced by an endogenous signalling molecule. D A substance that binds to a receptor and causes a greater response than that produced by an endogenous signalling molecule.