Self-Assessment Questions

42. Ovarian neoplasms

• Where do epithelial ovarian cancers generally spread, and how might these metastases manifest clinically?

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  Correct answer:
  They generally spread locally to the fallopian tube and uterus, and they also disseminate to the contralateral ovary and within the peritoneum. Cancer implants can be found in the cul-de-sac, bowel, mesentery, omentum and diaphragm. Ascites can be a consequence of these implants, thus leading to abdominal bloating as well as dyspepsia and urinary frequency from compression of organs.